KMID : 0363320210420040547
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Journal of Korean Oriental Internal Medicine 2021 Volume.42 No. 4 p.547 ~ p.562
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The Effect of Sayeok-san for Insomnia: A Systematic Review and Meta-Analysis
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Huh Tae-Young
Ha Da-Jung Kim Kyoung-Min
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Abstract
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Objectives: This study evaluated the effectiveness of Sayeok-san for treating insomnia.
Methods: We conducted a search using keywords, such as ¡°Sayeoksan", ¡°Si-ni-san", and ¡°insomnia" in eight databases (CNKI, Wanfang, Pubmed, Embase, Cochrane, NDSL, OASIS, RISS) on July 17, 2012. There was no limit placed on the publication period of the papers, and we used Cochrane¡¯s risk of bias tool to assess their quality. Meta-analysis was classified according to the outcome measurements, such as total effective rate and PSQI.
Results: Nine RCTs were selected. Meta-analysis showed that the treatment group, which used Sayeok-san, had a higher total effective rate than did the control group that used only Western medicine. The treatment group also had a lower average of PSQI and TSS (TCM symptom score) than did the control group.
Conclusion: This study suggests that Sayeok-san is effective in treating insomnia. However, these findings should be interpreted cautiously due to unknown or high risk of bias of the included trials.
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KEYWORD
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insomnia, sleep disorder, sini powder, si ni san, Sayeok-san
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