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KMID : 0368119920220010077
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Korean Circulation Journal
1992 Volume.22 No. 1 p.77 ~ p.86
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Usefulness of SPECT Thallium-201 Exercise Myocardial Perfusion Scan in Coronary Artery Disease
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최기준
최동주/손대원/정준기/이명묵/이명철/박영배/최윤식/서정돈
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Abstract
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To evaluate the usefullness of SPECT thallium-201 exercise myocardial perfusion scan in coronary artery disease. polar maps processing SPECt images were compared to the exercise treadmill tes tand the findings of coronary angiographies in 12
normal
subjects and 27 patients with the coronary artery disease.
@ES The following results were obtained:
@EN 1) Sensitivity and specificity of thallium-201 exercise myocardial perfusion scan was 96% and 83%. higher than that of exercise treadmill test (81% and 61%).
2) In the branches of coronary artery. the sensitivity. specificity and positive predicitive values were 82%, 88%, 90% in left anterior descending artery, 33%, 88%, 57% in left circumflex artery and 69%, 81%, 64% in right coronary artery.
3) The good correlation was observed between the degree of perfusion defect in polar map of thallium-201 myocardial scan in stress and 'myocardial ischemic score' predicted in coronary angiography (p<0.001). Also the degree of reversible
perfusion
defect had significant correlation with the duration of exercise.
4) The pulmonary to myocardial ratio of thallium-201 uptake in coronary artery disease group was higher than that of normal control group. especially that of postinfarct angina group higher than that of angina group. And the perfusion defect
with
stress and double product at maximal exercise had stroungest assocition with the pulmonary to mycardial ratio of thallium-201 uptake by stepwise multiple linear regression.
In conclusion. SPECT thallium-201 exercise myocardial perfusion scan is superior to the exercise treadmill test in diagnosing the coronary artery disease and is useful for predicting the sites and degree of coronary arterial stenosis. Also the
pulmonary
to mycoartdial ration of thallium-201 uptake is thought to be good new test index in evaluationg the left ventricular function of patients with coronary artery disease.
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KEYWORD
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