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KMID : 0368119920220030366
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Korean Circulation Journal
1992 Volume.22 No. 3 p.366 ~ p.379
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Serial Changes of Transmitral Inflow patterns after Acute Myocardial Infarction
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송우혁
김영훈/임도선/김혜경/안태훈/서홍석/심완주/노영무
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Abstract
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Background:
@EN Although determination of Doppler echoc ardiographic transmitral inflow patterns (DETIP) is used as an indirect method assessing LV diastolic function. it is known that DETIP can be affected by certain hemodynamic variables. The aim of this
investigation is to assess the serial changes of DETP and to determine the relation of DETIP with clinical parameters such as initial left ventricular end-diastalic volume (LVEDV). ejection fraction (EF). Killip class and thrombolytic therapy in
acute
myocardial infarction (AMI) patients.
@ES Method:
@EN Four serial Doppler and 2-D echocardiographic studies were performed at 1 day. 1 week. 1 mouth and 3 months after development of AMI in 24 patients (M:F=19:5. aged 58±11 year. 15 anterior MI and 9 inferior MI) and 13 normal adults (aged
47±9
years) as reference group. On admission 14 patients were in Killipo class I and 10 patients in class II.
Thrombolytic therapy with IV urokinase were done in 11 patients. E velocity. A velocity. pressure half-time (PHT). isovolumic relaxation time (IVRT) were analyzed and LV systolic function was determined in apical 4 chamber view.
@ES Results:
@EN DETIP did not change until 1 month after development of AMI. However. E/A ratio was decreased. and PHT and IVRT were increased at 3 months after AMI.
Doppler transmittral flow parameters were not related with Killip class and LV systolic function. Patients who received urokinase intravenously and who had greater initial LVEDV (>118 ㎤) showed higher E/A ratio and shorter PHT and IVRT than
those
who
did not. These findings indicate that changes in Doppler transmitral inflow pattern in AMI patients are not uniform over a period of 3 months and thrombolytic therapy causes favorable effect on Doppler transmitral flow parameters.
@ES Conclusion:
@EN Changes in Doppler transmitral inflow pattern may be variable over post-Ami period and this should be taken into account in evaluating LOV diastolic function after AMI. Thrombolytic therapy may improve LV diastolic function in AMI patients.
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KEYWORD
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