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KMID : 0368119920220040616
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Korean Circulation Journal
1992 Volume.22 No. 4 p.616 ~ p.625
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Clinical Value of Thallium-201 Reinjection for the Identification of Myocardial Viability in Patients with Coronary Artery Disease and Left Ventricular Dysfunction
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윤호중
윤광무/정욱성/백상홍/김종진/김재형/최규보/홍준소/박정미
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Abstract
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Bacground:
@EN The reinjection of a small dose of thallium-201 after stress and delayed imaging often shows new redistribution in the region with persistent defect.
The purpose of this study was to determine the incidence of incomplete redistribution on conventional delayed image and to compare the left ventricular wall motion abnormality with myocardial viability in patients with coronary artery disease.
@ES Methods:
@EN We studied 12 patients with chronic coronary artery disease. using exercies Thallium-201 Single Photon Emission Tomography (T1-201 SPECT) and coronary angiography with contrast ventriculography. Patients received 2mCi of thallium
intravenously
during exercies. redistribution images were performed 4 hour later and a second dose of lmCi of thallium was injected at rest immediately thereafter. The three sets of image (stress. redistribution and reinjection) were analyzed. The three sets
of
image(stress. redistribution and reinjection) were analyzed. The left ventricular myocardium was divided into 7 segments and regional wall motion wall motion was scored on scale from 2 (normal) to -1 (dyskinesis).
@ES Results:
@EN 1) The redistribution was obtained in 42.9% of the segments with persistent T1-201 defect on 4 hour delayed image.
2) Myocadial viability was observed in 38.9% of regions with wall motion abnormality on contrast ventriculography.
3) The wall motion score was lower in the segments with persistent T1-201 defect on reinjection image than those with transient defect (p<0.05).
4) In 42.9% of the regions with wall motion abnormality on contrast ventriculogradphy before coronary artery bypass graft. normal T1-201 image was observe dafter coronary artery bypass graft.
@ES Conclusion:
@EN Thallium-201 reinjection image can be used to identify viable myocardium in segments that demonstrate a persistent thallium defect on conventional delayed images in patients with chronic coronary artery disease and left ventricular
dysfunction.
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KEYWORD
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