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KMID : 0368119930230030474
Korean Circulation Journal
1993 Volume.23 No. 3 p.474 ~ p.480
A Case of Systemic Progressive Sclerosis After Cosmetic Surgery with Silicone Gel




Abstract
Human Adjuvant Disease (HAD) is a connective tissue disease occuring after cosmetic surgery with a foreign substance. In was first reported by Miyoshi in 1964. There have been specific connective disorders such as systemic lupus erythematosus.
rheumatoid arthritis. progressive systemic sclerosis, and mixed connective tissue disease. Scleroderma is the single most commonly reported disease.
A 55-year-old woman was seen for evaluation of dypnea. Four years previously. she underwent cosmetic surgery with silicone injected directly into eyelid, forehead, both hand and mons pubis. The patient presented the classic feature of systemic
sclerosis
and pericardial effusion. Following pericardiocentesis. she felt somewhat better and became less dyspneic. Seventeen days later, however,she progressively deteriorated and died in spite of intensive medical therapy and supportive case.
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