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KMID : 0368119940240010053
Korean Circulation Journal
1994 Volume.24 No. 1 p.53 ~ p.59
Intracoronary Ergonovine Provocation Test in Patients with Coronary Artery Spasm
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Abstract
Background :
@EN Intravenous ergonovine and intracoronary acetylcholine tests have been used to induce coronary artery spasm, however, potential problems with each test require a safer and more specific test.
@ES Methods :
@EN To evaluate the usefulness of the intracoronary ergonovine provocation test in patients with coronary artery spasm, this test was performed in 83 patients(male 47, female 36) with normal or near-normal looking coronary angiography or
insignificant
lesion less than 50% in diameter after routine diagnostic coronary angiography. Te micrograms of ergonovine maleate diluted in 1 ml of saline was injected into right coronary artery upto 2 times and into left coronary artery upto 3 times.
Induction
of
coronary arterial narrowing more than 75% of luminal diameter with typical chest pain and/or ECG changes in two or more adjacent leads was considered as a positive test.
@ES Results :
@EN Intracoronary ergonovine provocation tests were positive in 33 patients among 83 patients. In 24 patients, coronary artery spasm was induced in RCA, 12 patients in LAD and 8 patients in LCX. Coronary artery spasm of a sites was observed in 11
patients. In 27 patients, typical chest pain was developed with spasm. The ECG changes during spasm were ST elevation in 19 patients, ST depression in 3 patients. T wave change only in 2 patients and no change in 9 patients. The provocation tests
showed
focal spasm in 23 patients70%) and diffuse spasm in 10 patients(30%).
@ES Conclusion :
@EN Intracoronary ergonovine provocation test appears to be a safe and effective method to provoke the coronary artery spasm.
KEYWORD
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