We report a case of a 44 year old femele with unilateral aldosterone-proucing adrnal adenoma characterized by hypertension, plasma aldosterone excess, and low plasma renin, commonly but not invariably with hypokalemia. She also had asymmetric
septal
hypertrophy of left ventricle established with two-dimensional echocardiography. The electrocardiogram showed inverted T wave and prominent U wave with high QRS voltage on precordial leads. In the case of this patient, we are not sure whether
asymmetric
septal hypertrophy was caused by secondary hyypertension and chronic aldosterone excess of primary aldosteronism, or hypertrophic cardiomyopathy per se, so further long-term follow-up is required to determine it.
Following the successful unilateral adrenalectomy, however, the systemic pressure fell down to the normal level and electrolyte abnormalities were corrected immediaterly within a few days and the modest regression in septal hypertrophy was noted
in
one
year, suggesting that the primary aldosteronism contributes to the development or progression of asymmetric septal hepertrophy.
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