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KMID : 0368119990290050517
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Korean Circulation Journal
1999 Volume.29 No. 5 p.517 ~ p.522
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The Usefulness of Pericardial Biopsy to Evaluate the Causes of Pericardial Disease
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1박소영/1So Young Park
1김기식/1배장호/2김여희/1Kee Sik Kim/1Jang Ho Bae/2You Hee Kim
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Abstract
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Background and Objectives : The identification of a specific etiology of effusive
pericardial disease is difficult because of the limited yield of cytologic and microbiologic
pericardial fluid analysis. We performed retrospective study to fine out whether
pericardial biopsy was superior to pericardial fluid analysis in search of the etiology of
pericardial effusion.
Materials and Method : We reviewed 76 cases of moderate to sever pericardial effusion
on which we performed surgical pericardial biopsy from Sep. 1986 to Sep 1996. The
results of pericardial fluid analysis, clinical manifestation, pericardial biopsy were
compared retrospectively.
Results : 1) Clinical diagnosis of pericardial effusion were as follow ; neoplastic disease
(7.9%), tuberculosis (72.4%), constrictive pericarditis (17.1%), and others (2.6%).
2) By the percutaneous pericardial biopsy, we confirmed 19 cases (25%). Etiology of 4
cases (5.3%) were malignancy and 15 cases (19.7%) tuberculosis. Fifteen out of 76
patients who were diagnosed by biopsy as tuberculous pericarditis and 28 patients who
were suspected as tuberculous pericarditis clinically were treated with antituberculous
medications. Ten patients (66.7%) of pathologically diagnosed patients and 18 patients
(69.2%) of clinically diagnosed patients showed complete resolution of pericarditis.
Conclusion : By pericardial biopsy, we only confirmed 19 cases (25.0%). It means that
pericardial biopsy is not superior to pericardial fluid analysis in searching of etiology of
pericardial effusion. Moreover, it is not sufficient for final diagnosis of pericardial
effusion.
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KEYWORD
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