KMID : 0368119990290060635
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Korean Circulation Journal 1999 Volume.29 No. 6 p.635 ~ p.638
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A Case of Cardiac Chloroma Complicated by Acute Lymphocytic Leukemia
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1¹Ú¼öÁ¦/1Su Je Park
1±èÀμ·/1±è»ó¿í/1Á¤Ã¶¿ø/1±èÅÂÈ£/1·ù¿Õ¼º/1ÀÌ»óÀç/1À¯¾ðÈ£/2À̹̰æ/2¹Ú¾ÖÀÚ/1In Seop Kim/1Sang Wook Kim/1Chul Won Jung/1Tae Ho Kim/1Wang Seong Ryu/1Sang Jae Lee/1Un Ho Ryoo/2Mi Kyung Lee/2Ae Ja Park
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Abstract
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Chloroma (granulocytic sarcoma) indicates an extramedullary leukemic cell collection. It
often develops in the course of, or as a presenting sign of leukemia. Cardiac chloroma is
uncommon and rarely detected as a mass. We report the first case of cardiac chloroma
in a patient with acute lymphocytic leukemia in Korea. A 73-year-old man was
admitted because of exertional dyspnea, orthopnea and generalized weakness.
Thrombocytopenia and immature leukocytes were detected in the peripheral blood. An
X-ray film of the chest showed mild cardiomegaly and bilateral pleural effusion.
Transthoracic and transesophageal echocardiography showed a low echogenic mass at
the lateral wall of the right ventricle. The size of the mass was about 6¡¿4§¯. MRI of
the chest showed right ventricular mass with slightly increased inhomogeneous signal
intensity. Bone marrow aspiration and biopsy confirmed that he had a L3 FAB subtype
of acute lymphocytic leukemia. Induction chemotherapy with vincristine, prednisolone,
daunorubicin resulted in hematologic complete remission. At 6 weeks after the induction
chemotherapy, transesophageal echocardiography demonstrated disappearance of the right
ventricular mass which suggested that it was a cardiac chloroma complicating acute
lymphocytic leukemia.
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