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KMID : 0368119990290060635
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Korean Circulation Journal
1999 Volume.29 No. 6 p.635 ~ p.638
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A Case of Cardiac Chloroma Complicated by Acute Lymphocytic Leukemia
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1박수제/1Su Je Park
1김인섭/1김상욱/1정철원/1김태호/1류왕성/1이상재/1유언호/2이미경/2박애자/1In Seop Kim/1Sang Wook Kim/1Chul Won Jung/1Tae Ho Kim/1Wang Seong Ryu/1Sang Jae Lee/1Un Ho Ryoo/2Mi Kyung Lee/2Ae Ja Park
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Abstract
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Chloroma (granulocytic sarcoma) indicates an extramedullary leukemic cell collection. It
often develops in the course of, or as a presenting sign of leukemia. Cardiac chloroma is
uncommon and rarely detected as a mass. We report the first case of cardiac chloroma
in a patient with acute lymphocytic leukemia in Korea. A 73-year-old man was
admitted because of exertional dyspnea, orthopnea and generalized weakness.
Thrombocytopenia and immature leukocytes were detected in the peripheral blood. An
X-ray film of the chest showed mild cardiomegaly and bilateral pleural effusion.
Transthoracic and transesophageal echocardiography showed a low echogenic mass at
the lateral wall of the right ventricle. The size of the mass was about 6×4㎝. MRI of
the chest showed right ventricular mass with slightly increased inhomogeneous signal
intensity. Bone marrow aspiration and biopsy confirmed that he had a L3 FAB subtype
of acute lymphocytic leukemia. Induction chemotherapy with vincristine, prednisolone,
daunorubicin resulted in hematologic complete remission. At 6 weeks after the induction
chemotherapy, transesophageal echocardiography demonstrated disappearance of the right
ventricular mass which suggested that it was a cardiac chloroma complicating acute
lymphocytic leukemia.
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