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KMID : 0368120000300030365
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Korean Circulation Journal
2000 Volume.30 No. 3 p.365 ~ p.368
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A Case of Myocardial Injury after Phenylpropanolamine Ingestion
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윤원찬/Wern Chan Yoon
여동근/김학준/박정기/도준형/류재근/최지용/장성국/Dong Geun Yeo/Hak Jun Kim/Jeong Ki Park/Joon Hyung Doh/Jae Kean Ryu/Ji Yong Choi/Sung Gug Chang
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Abstract
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Pheylpropanolamine is a sympathomimetic amine used widely as a decongestant or
appetite suppressant. Reports of the myocardial injury from the use of
phenylpropanolamine are rare and the mechanism of the myocardial injury is not known
clearly. We experienced a case of myocardial injury after ingestion of
phenyl-propanolmine. A 46-year-old woman was admitted because of chest pain and
dyspnea after ingestion of 5 tablets of anorectic pill containing phenylpropanolamine 75
mg per tablet. The serum creatine kinase MB isoenzyme levels were elevated and
electrocardiographic abnormalities suggesting myocardial infarction were seen in the
precordial lead. In echocardiograpy, left ventricular anteroseptal wall motion was nearly
akinetic but coronary angiography showed normal coronary arteries except sluggish
blood flow in left anterior descending artery.
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KEYWORD
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