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KMID : 0368120020320121072
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Korean Circulation Journal
2002 Volume.32 No. 12 p.1072 ~ p.1077
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Left Ventricular Mass Measurement Using Tc-99m MIBI Myocardial Perfusion SPECT：Comparison with Echocardiographic Method
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배선근/Sun Keun Bae
안병철/이상우/정신영/양동헌/박헌식/조용근/이재태/채성철/전재은/박의현/이규보/Byeong Cheol Ahn/Sang Woo Lee/Shin Young Jeong/Dong Heon Yang/Hun Sik Park/Yong Geun Jo/Jae Tae Lee/Shung Chull Chae/Jae Eun Jun/Wee Hyun Park/Kyu Bo Lee
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Abstract
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Background and Objectives: A left ventricular mass (LVM) can be used as a prognostic factor in patients with cardiovascular disease, and echocardiographic LVM measurements are most commonly used. We have measured LVM using quantitativel gated myocardial perfusion SPECT (QGS), and compared these results with LVM measured by echocardiography.
Subjects and Methods: One hundred and sixteen subjects (M/F=66/50, mean age: 58 yrs) underwent both rest QGS with Tc-99m MIBI and echocardiography. On visual interpretation, thirty-six subjects (31%) showed perfusion defects. The myocardial volume was obtained using the AutoQUANT program, and the LVM (LVMSPECT) was calculated by multiplying the volume by the specific gravity of the myocardium. We also measured the echocardiographic LVM (LVMEcho) by the Devereux formula, within one month of the LVMSPECT.
Results: The LVMSPECT and LVMEcho were well correlated (r=0.717, p<0.001), but a significant difference was noted between the two values. The mean difference between the LVMSPECT and LVMEcho was 24 g. The LVMEcho was smaller than the LVMSPECT in those subjects with a small LVMEcho, and greater than the LVMSPECT in the subjects with a large LVMEcho. The difference between the LVMEcho and LVMSPECT (LVMEcho-LVMSPECT) was positively correlated with the LVMEcho (r=0.893, p<0.001).
Conclusion: The LVMs measured by gated myocardial perfusion SPECT and echocardiography were well correlated. But they were significantly different, especially in subjects with large LVMs.
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KEYWORD
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Hypertrophy, left ventricular, Radionulcide imaging, Echocardiography
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