KMID : 0368120080380030140
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Korean Circulation Journal 2008 Volume.38 No. 3 p.140 ~ p.143
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Noninvasive Pacemaker Stress Echocardiography as a Screening Test for Coronary Artery Disease in Patients With Atypical Angina and Permanent Pacemaker
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Yoon Hee-Jung
Seung Ki-Bae Kim Jae-Hyung Youn Ho-Joong Rho Tai-Ho Jin Seung-Won Lee Jong-Min Lee Man-Young Her Sung-Ho Do Kyong-Rock
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Abstract
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Background and Objectives: Making the noninvasive diagnosis of coronary artery disease in patients with a permanent pacemaker is difficult because of the inability to interpret electrocardiograms and the low specificity of perfusion scintigraphy. We evaluated the diagnostic accuracy of noninvasive pacemaker stress echocardiography (PASE) as a screening test for coronary artery disease in patients with atypical angina and a permanent pacemaker.
Subjects and Methods: This a prospective study, and transthoracic stress-pacing echocardiography was performed on 15 patients (9 men and 6 women; age, mean age: 71.1¡¾11.0 years) with atypical angina and a permanent pacemaker. All the patients underwent noninvasive pacemaker-stress echocardiography by external programming (pacing the heart rate up to 150 beats per minute). Coronary angiography was performed on the 8 patients with positive PASE results. Significant coronary artery disease was defined as ¡Ã70% stenosis in at least one major coronary artery.
Results: The echocardiographic images were interpretable for all the patients. No significant side effects were observed. The left ventricular systolic function was preserved in all the patients (left ventricular ejection fraction; 63.5¡¾8%). Only 5 (62.5%) of 8 patients showed significant coronary artery disease, as documented by coronary angiography.
Conclusion: Noninvasive PASE is a simple, rapid, safe and diagnostically efficient test for detecting coronary artery disease in patients with atypical angina and a permanent pacemaker. Larger studies are necessary to validate our findings.
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KEYWORD
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Stress echocardiography, Coronary stenosis, Cardiac pacemaker, Artificial
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