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KMID : 0368120080380100551
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Korean Circulation Journal
2008 Volume.38 No. 10 p.551 ~ p.556
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Relationship Between RR Intervals and Early Diastolic Mitral Annulus Velocities in Atrial Fibrillation Patients Who do not Have Significant Valvular Diseases
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Choi Yeo-Won
Kim Jeong-Eun
Cho Eun-Jung
Kim Eun-Young
Seo Ki-Woo
Lee Kyung-Heon
Lee Kwang-Je
Kim Sang-Wook
Kim Tae-Ho
Ko Hong-Sook
Kim Chee-Jeong
Ryu Wang-Seong
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Abstract
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Background and Objectives: Irregular RR intervals in atrial fibrillation (AF) results in beat to beat changes in hemodynamical parameters. Early diastolic mitral annulus velocity (E’) is one of the parameters that represent diastolic function of the left ventricle (LV). In this study, we have investigated the effects of continuous changes of systolic functions in AF on the diastolic functions of the LV.
Subjects and Methods: E’ (35-40 beats) was recorded in 31 AF patients that did not have significant valvular heart diseases. The relationships between preceding RR intervals (RR-1) or pre-preceding RR intervals (RR-2) and E’s were obtained using a logarithmic function.
Results: Slopes between RR-1 and E’ varied from -1.62 to 1.04 in total coordinates. In the logistic regression analysis patients with negative slopes were found to have a larger left atrial size than patients with positive slopes (5.5±0.67 cm vs. 4.9±0.56 cm, p=0.02). Slopes were negatively related with mean RR intervals in the Pearson correlation analysis (r=-0.40, p=0.028). Slopes between RR-2 and E’ were also variable and were not associated with other parameters.
Conclusion: Beat to beat changes in systolic functions derived from irregular RR intervals in AF had variable effects on diastolic functions among patients. The relationship between RR-1 and E’ was associated with LA sizes and mean RR intervals.
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KEYWORD
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Left ventricular functions, Atrial fibrillation, Electrocardiography, Pulsed Doppler echocardiography
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