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KMID : 0368120090390020071
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Korean Circulation Journal
2009 Volume.39 No. 2 p.71 ~ p.74
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Clinical Utility and Accuracy of Coaguchek® XS, a Reliable Alternative to Laboratory International Normalized Ratio Monitoring in Korean Patients With Atrial Fibrillation
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Kim Sung-Hea
Suh Soon-Yong
Kim Hyun-Joong
Han Seong-Woo
Jung Sang-Man
Ryu Kyu-Hyung
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Abstract
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Background and Objectives: To evaluate the accuracy and the clinical utility of the Coaguchek® XS, a portable point-of-care coagulometer, compared to standard laboratory methods in Korean patients
Subjects and Methods: We included 107 patients with atrial fibrillation on long-term oral warfarin therapy. The prothrombin time as expressed by the international normalized ratio (INR) was measured by the portable Coaguchek® XS system as well as standard laboratory methods. Agreement between the two methods was defined as a difference of less than 0.3 between the INR values.
Results: The INR determined by the portable Coaguchek® XS had excellent correlation with the values obtained by standard methods (r=0.984, p<0.01). The INR determined by the portable Coaguchek® XS tended to be high among the high INR group values (standard INR>3.0). There was a 91.6% agreement between the two methods. Only nine cases (8.4%) had a difference of more than 0.3; this was mainly noted in the high INR group.
Conclusion: The portable self-testing of the INR by the Coaguchek® XS might be a reliable alternative to hospital based laboratory testing in Korean patients.
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KEYWORD
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Atrial fibrillation, Prothrombin time
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