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KMID : 0368120120420100684
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Korean Circulation Journal
2012 Volume.42 No. 10 p.684 ~ p.691
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Transcatheter Aortic Valve Implantation: Early Experience in Korea
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Kim Won-Jang
Kim Young-Hak
Lee Jong-Young
Park Duk-Woo
Kang Soo-Jin
Lee Seung-Whan
Lee Cheol-Whan
Kim Dae-Hee
Song Jong-Min
Kang Duk-Hyun
Song Jae-Kwan
Park Seong-Wook
Park Seung-Jung
Kim Joon-Bum
Jung Sung-Ho
Choo Suk-Jung
Chung Cheol-Hyun
Lee Jae-Won
Sim Ji-Yeon
Choi In-Cheol
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Abstract
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Background and Objectives: Transcatheter aortic valve implantation (TAVI) was recently introduced in Korea. The present report describes the experience of early TAVI cases.
Subjects and Methods: Between March, 2010 and October, 2011, 48 patients with severe symptomatic aortic stenosis (AS) were screened at the Asan Medical Center to determine their suitability for surgical intervention. Of these, 23 were considered unsuitable and underwent TAVI. Procedural success rates, procedure-related complications, and clinical outcomes were evaluated in the TAVI patients.
Results: Transfemoral (n=20) or transapical (n=3) TAVI was performed. The mean age of patients was 75.9±5.4 years and 57% were females. The mean logistic European System for Cardiac Operative Risk Evaluation was 25.6±5.1%. Implantation was successful in 22 patients (19 transfemoral, three transapical). After successful implantation, the mean aortic valve area increased from 0.68±0.14 cm2 to 1.45±0.33 cm2. There were no procedure-related complications or mortality. The patients showed no paravalvular aortic regurgitation with ≥ moderate degree and remained stable without progression during follow-up. During follow-up (interquartile range, 1.1-12.9), all patients were alive without any occurrence of valve failure.
Conclusion: TAVI procedure is feasible in patients with inoperative symptomatic AS leading to hemodynamic and clinical improvement. With accumulation of experience, proper patient selection and development of device technologies, TAVI should decrease adverse events and expand the indications in the near future.
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KEYWORD
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Aortic stenosis, Valve prosthesis
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