KMID : 0368120130430070500
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Korean Circulation Journal 2013 Volume.43 No. 7 p.500 ~ p.503
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A Delayed, Unusual Non-Cardiogenic Pulmonary Edema after Intravascular Administration of Non-Ionic, Low Osmolar Radiocontrast Media for Coronary Angiography
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Kang Min-Ho
Nah Jong-Chun
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Abstract
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Non-cardiogenic pulmonary edema (NCPE) is a rare adverse reaction to iodinated radiocontrast media (RCM), in which all previous cases were immediate reactions. A 56-year-old male was given iopamidol, a non-ionic, low osmolar RCM, during coronary artery angiography. He developed pulmonary edema and fever a day after the procedure. Despite diuretic therapy, the patient¡¯s pulmonary edema worsened and his high fever persisted. The patient¡¯s pulmonary edema was eventually resolved with intravenous steroid treatment. We interpreted the patient¡¯s condition as NCPE manifesting as a delayed reaction to RCM. To our knowledge, our case is the first to show NCPE as a delayed hypersensitivity reaction.
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KEYWORD
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Pulmonary edema, Hypersensitivity, Contrast media
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