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KMID : 0368120150450020141
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Korean Circulation Journal
2015 Volume.45 No. 2 p.141 ~ p.148
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Effects of Age, Sex, and Menopausal Status on Blood Cholesterol Profile in the Korean Population
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Park Ji-Hye
Lee Myung-Ha
Shim Jee-Seon
Cho Dong-Phil
Song Bo-Mi
Lee Seung-Won
Choi Han-Sol
Kim Hyeon-Chang
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Abstract
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Background and Objectives: To investigate age-specific and sex-specific distributions of blood cholesterol in the general Korean population.
Subjects and Methods: We analyzed data for 8284 men and 9246 women aged ≥10 years who participated in the fifth (2010-2012) Korea National Health and Nutrition Examination Survey. Age-specific means, medians, and selected percentiles were calculated for men, premenopausal women, and postmenopausal women.
Results: Median total cholesterol (TC) level increased with age across all age groups, from 147 to 196 mg/dL in males and from 159 to 210 mg/dL in females. Triglyceride (TG) levels increased with age in females; however, in males, TG levels rapidly increased during young adulthood, peaked at 50-54 years, and then decreased. High density lipoprotein-cholesterol (HDL-C) levels were higher in females than in males and decreased with increasing age in both males and females. Low density lipoprotein-cholesterol (LDL-C) levels increased with age across all age groups, from 89 to 127 mg/dL in males and from 82 to 113 mg/dL in females. Lipoprotein-cholesterol fraction (TC/HDL-C, LDL-C/HDL-C, TG/HDL-C, non-HDL-C) levels increased with age in females, but increased more rapidly in males during young adulthood and decreased after middle age.
Conclusion: Blood cholesterol levels and lipoprotein-cholesterol fractions present different distributions by age, sex, and menopausal status.
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KEYWORD
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Cholesterol, Triglycerides, High density lipoprotein-cholesterol, Low density lipoprotein-cholesterol, Epidemiology
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