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KMID : 0368120210510090752
Korean Circulation Journal
2021 Volume.51 No. 9 p.752 ~ p.763
Community-Dwelling Individuals with Coronary Artery Disease Have Higher Risk of Depression than the General Population in Female, But Not in Male
Kim Nam-Ho

Lee Young-Hoon
Kim Mi-Na
Abstract
Background and Objectives: The aim of this study was to assess sex difference in the association between coronary artery disease (CAD) status and depression in a representative nationwide Korean population.

Methods: In total, 4,620 male and 6,151 female aged ¡Ã40 years, who participated in the Korea National Health and Nutrition Examination Survey conducted in 2014, 2016, and 2018, were included in the analysis. Depression was defined as ¡Ã10 points on the 9-item Patient Health Questionnaire.

Results: Among male participants, no significant association between CAD status and depression was observed. However, female with CAD had higher odds ratio (OR) for depression (OR, 2.68; 95% confidence interval [CI], 1.78?4.03) compared with those without CAD in a multiple logistic regression analysis after adjustment for covariates. Younger age at diagnosis of CAD was a significant relating factor for depression in female; OR (95% CI) was 1.73 (0.88?3.40), 3.01 (1.52?5.97), and 4.11 (2.04?8.28) for age ¡Ã65 years, 55?64 years, and ¡Â54 years, respectively, compared with that in non-CAD controls. In addition, shorter duration of CAD was a significant relating factor for depression in female; OR (95% CI) was 2.42 (1.26?4.67), 2.61 (1.32?5.16), and 3.13 (1.54?6.34) for duration ¡Ã10 years, 5-9 years, and ¡Â4 years, respectively, compared with that in non-CAD controls.

Conclusions: Consistent screening and psychosocial supports for depression after discharge are required to improve the mental health care of CAD survivors in the community, especially for female diagnosed at a younger age and recently diagnosed.
KEYWORD
Coronary artery disease, Depression, Patient Health Questionnaire, Community
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