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KMID : 0370220140580060364
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Yakhak Hoeji
2014 Volume.58 No. 6 p.364 ~ p.370
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Ameliorating Effect of Herbal Extracts Mixtures of Laurus nobilis, Rosa roxburghii and Opuntia ficus indica on Ethanol Induced Psychomotor Alterations in Rats
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Kim Hee-Jin
Irene Joy I. dela Pena
Yoon Seo-Young
Jun Bryan de la Pena
Paek Se-Hee
Seo Yong-Ki
Park Seok-Jun
Moon Byoung-Seok
Cheong Jae-Hoon
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Abstract
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The aim of this study was to find optimal ratio of herbal extracts to ameliorate ethanol-induced psychomotor alterations. Four mixtures of Laurus nobilis (L. nobilis), Rosa roxburghii (R.R.) and Opuntia ficus indica (OFI) were pretreated 30 minutes before ethanol administration in rats. Behavioral activities were evaluated. Blood ethanol and acetaldehyde levels were also measured. These effects of mixture of R.R (50 mg/kg)+OFI (100 mg/kg)+L.nobilis (100 mg/kg) were better than those of other mixtures. This mixture could be used as an effective substance to develop a functional food.
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KEYWORD
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Laurus nobilis, Rosa roxburghii, Opuntia ficus indica, ethanol, behavioral, psychomotor
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