KMID : 0370919920090020342
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Yeungnam Univercity Journal of Medicine 1992 Volume.9 No. 2 p.342 ~ p.350
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Gastric Mucosal Damage by Bile Acid
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Abstract
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To investigate the effect of bile acid on gastric mucosa, we performed biologic test using Sprague-Dawley rat. Mixture solution of TDCA 15mM and Hcl of pH 3 was given into stomach to one group and HCl of pH 3 was given into stomach to another
group. The
significant gastric mucosal change was vasodilation and edema, that was disappeared progressively. These findings suggest the bile acid and damage gastric mucosa.
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KEYWORD
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