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KMID : 0371420211000020076
Annals of Surgical Treatment and Research
2021 Volume.100 No. 2 p.76 ~ p.85
Effect of Enhanced Recovery After Surgery program on hospital stay and 90-day readmission after pancreaticoduodenectomy: a single, tertiary center experience in Korea
Kim Doo-Hun

Yoon Yoo-Seok
Han Ho-Seong
Cho Jai-Young
Lee Jun-Seo
Lee Bo-Ram
Abstract
Purpose: Despite increasing number of reports on Enhanced Recovery After Surgery program (ERAS) and readmission after pancreaticoduodenectomy (PD) from Western countries, there are very few reports on this topic from Asian countries. This study aimed to evaluate the effects of ERAS on hospital stay and readmission and to identify reasons and risk factors for readmission after PD.

Methods: This retrospective cohort study included 670 patients who underwent open PD from January 2003 to December 2017. The patients were classified into ERAS (n = 352) and non-ERAS (n = 318) groups. Patients' characteristics, perioperative outcomes, and readmission rates were compared.

Results: There were no significant differences in the postoperative complication rates between the groups. The mean postoperative hospital stay was significantly shorter in the ERAS group (24.5 vs. 18.0 days, P < 0.001), but the 90-day readmission rate was similar in the 2 groups (9.1% vs. 8.5%, P = 0.785). Complications associated with pancreatic fistula (42.4%) were the most common cause for readmission. In the multivariate analysis, diabetes mellitus (odds ratio [OR], 1.84; 95% confidence interval [CI], 1.05?3.24; P = 0.034), preoperative non-jaundice (OR, 0.45; 95% CI, 0.25?0.82; P = 0.009) and severe postoperative complications (OR, 4.12; 95% CI, 2.34?7.26; P < 0.001) were identified as risk factors for readmission.

Conclusion: The results confirmed that the ERAS program for PD was beneficial in reducing postoperative stay without increasing readmission risks. To decrease readmission rates, prudent discharge planning and medical support should be considered in patients who experience severe complications.
KEYWORD
Enhanced Recovery After Surgery, Length of stay, Korea, Pancreaticoduodenectomy, Patient readmission
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