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KMID : 0374019830060020065
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Ewha Medical Journal
1983 Volume.6 No. 2 p.65 ~ p.70
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The Alterations of Na^(＋)·K^(＋)-ATPase Activity and Concentrations of ATP Following Experimental Spinal Cord Trauma
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Abstract
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The author measured the activities of the membrane- bound enzyme, Na+ - K+-ATPase, and ATP as a part of an attempt to define the major cellular alterations in the initial 4-hour period of the feline spinal cord following experimental impa ct injury with 400gm -- cm. The activities of Na+ - K+ ATP ase were significantly decreased at post-injury 1-hour and between the 1-hour and 4-hour period. But for these same samples, the activities of Mg z+ - ATP ase did not change appreciably Contents of ATP were, significantly depleted in the same period. These changes suggested that this model of the spinal cord trauma results in a severe
_irrevirsible injury to the affected tissues.
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