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KMID : 0374019930160010008
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Ewha Medical Journal
1993 Volume.16 No. 1 p.8 ~ p.8
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Evaluation of Microparticle Enzyme Immunoassay (MEIA) (IMRX, Abbott) in the Determination of Serum Thyrotropin (TSH)
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Abstract
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Microparticle enzyme immunoassay (MEIA) for thyrotropin (TSH) was evaluated and results were compared with those of immunoradiometric assay (IRMA) procedure Coefficient of variations of within day precision was 3.8-9.6% and those of between day
precision was 3.6-17.2% Correlation beween the MEIA(Y) and two site IRMA(X) was excellent (Y=1.0445X-0.1538. r=0.9948). The sensitivity of the assay (mean±2 SD of the zero standard) was 0.0158μIU/ml The concentration measured measured in 497
healthy
subjects were ranged from 0.2-3 μIU/ml (mean 1.37μIU/ml. SD 0.59)
Conclusively, MEIA is more fully automated than IRMA, well correlated with IRMA. can be reliable method for screening test of thyroid function.
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KEYWORD
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