KMID : 0377519780030010053
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Chung-Ang Journal of Medicine 1978 Volume.3 No. 1 p.53 ~ p.58
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On the ¥á-Glycerophosphate Dehydrogenase from Human term Placenta
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Lee Keun-Dae
Lee Hi-Sung Lee Keun-Bai
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Abstract
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Human term placenta was fractionatted by differential centrifugation into cytoplasmic and mitochondrial fraction. The activity of cytoplasmic ¥á-glycerophosphate dehydrogenase (G3P oxidoreductase (EC 1.1.1.94 : G3P : NAD 2-oxidoreductase)) was assayed according to the method of Gonzalez-Cerezo and the activity of mitochondrial ¥á-glycerophosphate dehydrogenase (G3P dehydrogenase (EC 1.1.99.5 : G3P : cytochrome oxidoreductase)) was determined by the procedure of Dawson and Thorne. Unusually high rate of ¥á-glycerophosphate oxidation was found both in cytoplasm and in mitochondria. Despite the disparity of results by some authors, the present finding strongly suggests that the ¥á-glycerophosphate shuttle system operates actively in human term placenta.
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