KMID : 0377519980230040187
|
|
Chung-Ang Journal of Medicine 1998 Volume.23 No. 4 p.187 ~ p.196
|
|
An immunohistochemical observation of the expression of transforming growth factor-¥â_2 and -¥â_3 in the eye of rat fetus
|
|
Kim Yong-Wook
Lee Won-Bok Kim Kyung-Yong Choi Jeong-Kyu
|
|
Abstract
|
|
|
The expression of the transforming growth factor(TGF)-¥â_2 and ¡¤¥â_3 was studied in the eye of fetal rats by immunohistochemistry. The results obtained were as follows. The TGF-¥â_2 and¡¤¥â_3 expressed in almost all parts of the eye, exhibited the localization in the same areas as well as the localization specific to each isoforms, which indicated the roles of TGF-¥â_2 and TGF-¥â_3 were partly dependent on each other. TGF-¥â_2 showed the characteristic expression pattern in neuroepithelial layer of retina and les cell. TGF-¥â_3 showed characteristic expression in pigment layer of retina as well as in lens cell. TGF-¥â_2 exhibited strong and characteristic expression pattern and seemed to have more important role than TGF-¥â_3 in eye formation. In summary, the expression of TGF-¥â_2 and¡¤¥â_3 in the development of the eye was observed in almost all parts, such as iris, lens, retina, and aqueous humor and seemed to play a role in the formation of eyes at fetal life.
|
|
KEYWORD
|
|
rat feral eye, TGF-¥â_2, ¥â_3
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|