KMID : 0378019730160090043
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New Medical Journal 1973 Volume.16 No. 9 p.43 ~ p.47
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Growth of Russian Spring-Summer Encephalitis Virus in Established Lines of Mosquito Cells
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ì°æÐ÷»/Lee, Yun-Tai
ÑÑÌ×â×/ì°ëÈìí/ÑÑÙ¥â×/ì°ðúýº/Kim, Kyung-Sook/Lee, Yoon-Il/Kim, Myoung-Suk/Lee, Chong-Hoon
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Abstract
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Growth of Russian spring-summer encephalitis virus in established line of mosquito (Sigh¢¥s Aedes albopictus) cells was studied by infectivity ¢¥ titration of mouse lethal doses and observation of morphological changes on the infected cell monolayers.
The cell line could support the multiplication of Russian spring summer encephalitis virus. The maximum virus titer of 10¢¥¢¥0 mice LD50 was reached in 3 days after virus inoculation. Cytopathic effect was found on the whole monolayer from second post infective day and large round spherical cell aggregates were observed theereafter.
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KEYWORD
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