Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.
KMID : 0379520210370020261
Çѱ¹µ¶¼ºÇÐȸÁö
2021 Volume.37 No. 2 p.261 ~ p.275
Hepatoprotective effect of Centella asiatica 50% ethanol extract against acetaminophen-induced acute liver injury in BALB/c mice
Park Dae-Won

Jeon Hye-Lin
Kwon Jeong-Eun
Lee Young-Geun
So Ri-Na
Choe Tae-Hwan
Jeong Yong-Joon
Kang Se-Chan
Abstract
N-acetyl-p-aminophenol (acetaminophen, APAP) is a well-known component of analgesic and antipyretic monotherapy products. However, exceeding the recommended dose can lead to serious injury to the liver. We conducted this study to determine the potential of Centella asiatica as a natural substance to protect against APAP-induced liver injury. When acute hepatotoxicity was induced in mice by APAP overdose, their liver weight decreased significantly (p?
KEYWORD
Centella asiatica, Triterpenoids, Asiaticoside, N-acetyl-p-aminophenol, Acute liver failure, Hepatoprotective activity
FullTexts / Linksout information
 
Listed journal information
ÇмúÁøÈïÀç´Ü(KCI) KoreaMed