KMID : 0380020080230020125
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Korean Journal of Biotechnology and Bioengineering 2008 Volume.23 No. 2 p.125 ~ p.130
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Biological activities of ethanol extract from the seawater algae, Chlorella elliposidea C020
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Kim Hyun-Jin
Kim In-Hae Lee Jae-Hwa
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Abstract
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We investigated the biological activities of ethanol extract from the seawater algae, Chlorella elliposidea C020 such as antibacterial activity, anti-oxidant activity, tyrosinase inhibitory activity and hemolytic activity against human erythrocytes. Extract was obtained from various solvent, methanol, ethanol, acetone and ethanol + acetone (1:1, v/v%), 95% ethanol proved to be best extraction solvents. The contents of ethanol extract were higher in freeze-dried sample than that in frozen-thawing. Antibacterial activities of ethanol extract showed strong inhibitory effect against Bacillus subtilis PM125, Bacillus licheniformis and fish pathogenic bacteria, Vibrio parahaemolyticus KCTC2471 and Edward tarda NUF251. However, this extract didn¡¯t worked against antifungal activity against Candida albicans KCTC1940. And, ethanol extract was without hemolytic activity against human erythorocytes. The ethanol extract showed 75% of free radical scavanging effect on 2.0 mg/mL using DPPH method. In tyrosinase inhibition assay of ethanol extract, (Inhibition Concentration) was measured as 10.87 mg/mL. Conclusionally, ethanol extract of Chlorella elliposidea C020 has good candidate for bioactive materials.
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KEYWORD
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Chlorella elliposidea C020, antibacterial activity, antioxidant activity, DPPH, tyrosinase inhibitory activity
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