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KMID : 0425120010390020197
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Parasites, Hosts and Diseases
2001 Volume.39 No. 2 p.197 ~ p.199
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Prevalence of arthropod antibodies in Korean patients with allergic rhinitis
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Hae Seon Nam/Kyu Yoon Hwang
Joon Soo Park/Hyun Cheol Ahn/Hae Seon Nam
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Abstract
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Arthropod antigens are main causative agents which induce allergic reponses in humans. However, little information is known about the prevalence of specific arthropod allergens in Koreans with allergic diseases. The current study was designed to determine the positive rates of arthropod antibodies by the Korean inhalant panel of MAST-CLA. One hundred sixty patients, who were diagnosed with allergic rhinitis from an out-patient center at the Soonchunhyang University Chunan Hospital, were studied between August 1998 to July 2000. The overall positive rate, at least more than one specific antibody of arthropods such as Dermatophagoides farinae (Df), Dermatophagoides pteronyssinus (Dp), and cockroach mix (Cm), was 46.9%. Each positive rate of Df, Dp, and Cm was 45.0%, 43.1%, and 8.8%, respectively. A significant agreement among arthropod allergens was observed (Df and Dp: 95.6%, Kappa = 0.911, P < 0.001). Our data supported the fact that arthropods were the most common allergens in Korean patients with allergic rhinitis; however, the MAST-CLA should be modified to increase specificity of arthropod allergens.
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KEYWORD
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arthropods, hypersensitivity, mites, cockroaches, allergic rhinitis,
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