|
KMID : 0425120080460020071
|
|
Parasites, Hosts and Diseases
2008 Volume.46 No. 2 p.71 ~ p.75
|
|
|
Antibody Responses to Cryptosporidium Antigen in HIV-positive Patients in the Republic of Korea
|
|
Guk Sang-Mee
Chai Jong-Yil
Shin Yung-Oh
Seo Min
|
|
|
Abstract
|
|
|
|
The diagnosis of cryptosporidiosis has been carried out using coprologic techniques in the Republic of Korea. However, antibody responses to Cryptosporidium have rarely been studied. Serum antibodies from HIV-positive/oocyst-positive Korean patients recognized significantly 31 and 27 kDa antigens, and HIV-negative/oocyst-positive individuals clearly reacted to 15/17 kDa antigens. Compared with oocyst-positive cases, 18.7% and 75.8% of sera from HIV-positive patients reacted to 31 and 27 kDa antigens. Only 11.1% of HIV-negative individuals reacted to 15/17 kDa. Based on these findings, serum antibody responses were different between HIV-positive and HIV-negative individuals infected with Cryptosporidium, and it is suggested that HIV-positive patients are more frequently exposed to C. parvum compared to HIV-negative individuals.
|
|
|
KEYWORD
|
|
|
Cryptosporidium parvum, serologic response, antigenic protein, HIV
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
    
|