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KMID : 0425120080460030175
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Parasites, Hosts and Diseases
2008 Volume.46 No. 3 p.175 ~ p.177
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Successful Treatment of Lupoid Cutaneous Leishmaniasis with Glucantime and Topical Trichloroacetic Acid (A Case Report)
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Nilforoushzade Mohamad Ali
Sadeghian Giti
Jaffary Fariba
Ziaei Hengameh
Shirani-Bidabad Liela
Mahzoni Parvin
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Abstract
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Lupoid leishmaniasis is a unique form of cutaneous leishmaniasis characterized by unusual clinical features and a chronic relapsing course, mostly caused by infection with Leishmania tropica. In this clinical form, 1-2 yr after healing of the acute lesion, new papules and nodules appear at the margin of the remaining scar. Herein, we describe a case of this clinical form that was resistant to 2 courses of treatments: systemic glucantime and then a combination therapy with allopurinol and systemic glucantime. However, marked improvement was seen after a combination therapy with topical trichloroacetic acid solution (50%) and systemic glucantime, and there were no signs of recurrence after 1 yr of follow-up.
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KEYWORD
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Leishmanis tropica, cutaneous leishmaniasis, trichloroacetic acid
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