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KMID : 0425120090470000059
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Parasites, Hosts and Diseases
2009 Volume.47 No. 0 p.59 ~ p.68
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Functional Genes and Proteins of Clonorchis sinensis
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Kim Tae-Im
Na Byoung-Kuk
Hong Sung-Jong
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Abstract
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During the past several decades, researches on parasite genetics have progressed from biochemical and serodiagnostic studies to protein chemistry, molecular biology, and functional gene studies. Nowadays, bioinformatics, genomics, and proteomics approaches are being applied by Korean parasitology researchers. As for Clonorchis sinensis, investigations have been carried out to identify its functional genes using forward and reverse genetic approaches and to characterize the biochemical and biological properties of its gene products. The authors review the proteins of cloned genes, which include antigenic proteins, physiologic and metabolic enzymes, and the gene expression profile of Clonorchis sinensis.
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KEYWORD
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Clonorchis sinensis, functional genes, chromosome, antioxidant enzyme, protease, energy metabolism, antigenic proteins
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