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KMID : 0425120120500020133
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Parasites, Hosts and Diseases
2012 Volume.50 No. 2 p.133 ~ p.136
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Visceral Leishmaniasis Mimicking Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Systemic Lupus Erythematosus Overlap
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Ozlem Guzel Tunccan
Abdurrahman Tufan
Gulcin Telli
Nalan Akyurek
Merve Pamukcuoglu
Guldal Yilmaz
Kenan Hizel
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Abstract
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Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena. To date, VL mimicking or exacerbating various autoimmune diseases have been described, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and autoimmune hepatitis (AIH). Herein, we presented a patient with VL who had overlapping clinical features with SLE, AIH, as well as antimitochondrial antibody (AMA-M2) positive primary biliary cirrhosis.
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KEYWORD
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Leishmania, visceral leishmaniasis, systemic lupus erythematosus, autoimmune hepatitis, primary biliary cirrhosis
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