|
KMID : 0578319930030020149
|
|
Molecules and Cells
1993 Volume.3 No. 2 p.149 ~ p.152
|
|
|
Importance of the Activation of Na+/H+ antiporter in Serum stimulated Proliferation
|
|
Moon soon-Ok
Kim Hyun-Bae
|
|
|
Abstract
|
|
|
|
To investigate the importance of the activation of Na+/H+ antiporter induced by serum, we used monensin, a carboxylic ionophore which stimulates Na+/H+ exchange across the plasma membrane and amiloride, inhibitor of Na+/H+ antiporter. We observed that monensin stimulated the transcription of c fos and c-myc, which are required for the cells to proceed Go to G, phase. These findings suggest that Na+/H+ antiporter may have important role in signal transduction pathway induced by serum.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|