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KMID : 0578319950050010001
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Molecules and Cells
1995 Volume.5 No. 1 p.1 ~ p.8
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Activation of and Signal Generation by Membrane Receptors
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Ji, Tae H.
Oh, Myung Suk/Koo, Yong Bum/Ji, InHae
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Abstract
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Many extracellular messengers interact with discriminate receptors on the cell surfacc. Somc of bound ligands activate receptors whereas others fail to do so. Only activated receptors are capable of generating signal and transducing it through the membrane. Recent advances in our understanding of agonist-induced and constitutive receptor activation suggest several molecular mechanisms for receptor activation, signal generation and transmembrane signal transfer.
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