|
KMID : 0578320140370010009
|
|
Molecules and Cells
2014 Volume.37 No. 1 p.9 ~ p.16
|
|
|
ADP-Ribosylation: Activation, Recognition, and Removal
|
|
Nan Li
Junjie Chen
|
|
|
Abstract
|
|
|
|
ADP-ribosylation is a type of posttranslational modification catalyzed by members of the poly(ADP-ribose) (PAR) polymerase superfamily. ADP-ribosylation is initiated by PARPs, recognized by PAR binding proteins, and removed by PARG and other ADP-ribose hydrolases. These three groups of proteins work together to regulate the cellular and molecular response of PAR signaling, which is critical for a wide range of cellular and physiological functions.
|
|
|
KEYWORD
|
|
|
ADP-Ribosylation, PARG, PARP, PAR recognition domain
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|