|
KMID : 0578320160390080639
|
|
Molecules and Cells
2016 Volume.39 No. 8 p.639 ~ p.644
|
|
|
Combined Detection of Serum IL-10, IL-17, and CXCL10 Predicts Acute Rejection Following Adult Liver Transplantation
|
|
Kim Na-Young
Yoon Young-In
Yoo Hyun-Ju
Tak Eun-Young
Ahn Chul-Soo
Song Gi-Won
Lee Sung-Gyu
Hwang Shin
|
|
|
Abstract
|
|
|
|
Discovery of non-invasive diagnostic and predictive biomarkers for acute rejection in liver transplant patients would help to ensure the preservation of liver function in the graft, eventually contributing to improved graft and patient survival. We evaluated selected cytokines and chemokines in the sera from liver transplant patients as potential biomarkers for acute rejection, and found that the combined detection of IL-10, IL-17, and CXCL10 at 1-2 weeks post-operation could predict acute rejection following adult liver transplantation with 97% specificity and 94% sensitivity.
|
|
|
KEYWORD
|
|
|
acute rejection, biomarker, chemokine, cytokine, liver transplant
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|