KMID : 0620719970030010042
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Natural Product Sciences 1997 Volume.3 No. 1 p.42 ~ p.48
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Alkaloids from The Roots of Tabernaemontana Macrocarpa Jack
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Husain Khairana
Said Ikram M. Din Laily B. Takayama Hiromitsu Kitajima Mariko Aimi N.
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Abstract
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The roots of Tabernaemontana macrocarpa Jack (Apocynaceae) yielded nine indole alkaloids which were identified as coronaridine (2), voacangine hydroxy-indolenine (3), 3-oxo-coronaridine (4), 19-R-heyneanine (7), coronaridine pseudoindoxyl (8) and voacangine pseudoindoxyl (9) while 3-(2-oxopropyl)-coronaridine (1), 3-(2-oxopropyl)-coronaridine-pseudoindoxyl (5) and 3-(2-oxopropyl)-voacangine-pseudoindoxyl (6) were isolated as artefacts formed during the isolation process. All of the alkaloids were identified by spectroscopic methods (UV,MS,©öH-NMR & ©ö©øC-NMR) and in comparison with the literature data.
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KEYWORD
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Tabernaemontana macrocarpa, Apocynaceae, roots, indole alkaloids, Iboga-type alkaloid
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