KMID : 0620719980040020091
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Natural Product Sciences 1998 Volume.4 No. 2 p.91 ~ p.94
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Studies on the Anti - inflammatory Effects of Drymaria cordata Willd
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Saha, B . P .
Pal, M ./Mukherjee, Pulok K ./Mukherjee, Kakali/Bhattacharya, S .
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Abstract
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In folklore medicine Drymaria cordata Willd (Family-Caryophyllaceae) is reported to have laxative and anti-febrile properties along with anti-inflammatory activities. Sikkimis used this plant to treat all these ailments. The anti-inflammatory effect of the methanol extract of D. cordata was investigated against carrageenin, histamine, serotonin, dextran and PGE©û induced rat hind paw oedema. It exhibited significant anti-inflammatory activity against all these phlogestic agents except PGE©û in the order of carrageenin $gt; serotonin $gt; histamine. All these effects were compared with standard drug phenylbutazone in both the acute and chronic experimental models in albino rats.
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