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KMID : 0620719990050020065
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Natural Product Sciences
1999 Volume.5 No. 2 p.65 ~ p.69
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Cyclooxygenase-2 Inhibitor from Evodia rutaecarpa
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Kang, Sam Sik
Son, Kun Ho/Kim, Ju Sun/Kim, Hyun Pyo/Chang, Hyeun Wook
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Abstract
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By bioassay guided fractionation followed by chromatographic separation of the MeOH extract from the fruit of Evodia rutaecarpa (Juss.) Benth. (Rutaceae), a new cyclooxygenase-2 inhibitor was isolated and identified as an alkaloid, rutaecarpine. Other alkaloids such as evodiamine and dehydroevodiamine together with limonoids were also isolated and characterized.
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