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KMID : 0620719990050040162
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Natural Product Sciences
1999 Volume.5 No. 4 p.162 ~ p.164
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Anti-HIV Activity of Dehydroaltenusin - a Metabolite from a Streptomyces sp .
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Jabbar, Abdul
Shresta, Ajude Prashad/Hasan, Choudhury Mahmood/Rashid, Mohammad Abdur
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Abstract
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Dehydroaltenusin (1) was isolated from the chloroform extract of the culture filtrate of a Streptomyces sp. and its structure was determined from spectral data as well as by comparison with published values. In an XTT-based in vitro anti-HIV assay, dehydroaltenusin effectively inhibited the cytopathic effects of HIV infection at a concentration of 1-5 ㎍/mL.
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