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KMID : 0620720000060010031
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Natural Product Sciences
2000 Volume.6 No. 1 p.31 ~ p.35
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Immunomodulatory Effect of Acidic Polysaccharide Fraction from Korean Red Ginseng (Panax ginseng)
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Park Kyeong-Mee
Jeong Tae-Cheon
Kim Young-Sook
Shin Han-Jae
Nam Ki-Yeul
Park Jong-Dae
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Abstract
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Effects of red ginseng acidic polysaccharides (RGAP) on immune system were studied. The proliferation of spleen cells was induced by RGAP treatment per se. Cotreatment of lipopolysaccharide (100 ㎍/ml) or concanavalin A (1 ㎍/ml) with RGAP further stimulated the spleen cell proliferation. BALB/c mice treated with RGAP showed a slight splenic hyperplasia and increased antibody forming cell response to sheep red blood cells. Flow cytometry analysis revealed an influx of macrophages in the mice treated with RGAP.
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KEYWORD
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Panax ginseng, red ginseng, acidic polysaccharide, antibody forming cell, macrophage
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