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KMID : 0620720000060020053
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Natural Product Sciences
2000 Volume.6 No. 2 p.53 ~ p.55
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Isolation and Anti-thrombotic Activity of Citric acid 1,5-dimethyl ester from Gastrodia elata
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Yun-Choi, Hye Sook
Park, Kyung Mi/Pyo, Mi Kyung
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Abstract
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In the course of continous work for the discovery of anti-thrombotic constituents from tubers of Gastrodia elata, citric acid 1,5-dimethyl ester was isolated from ethylacetate soluble fraction prepared from the methanol extract. The structure of the compound was determined by the spectroscopic data. The anti-thrombotic effect of this compound was observed with prolonging the bleeding time in thrombin-induced thrombosis model of mice.
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