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KMID : 0620720010070030090
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Natural Product Sciences
2001 Volume.7 No. 3 p.90 ~ p.93
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The Effect of Opuntia ficus - indica var. saboten Fruit on Gastric Lesion and Ulcer in Rats
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Lee, Eun Bang
Hyun, Jin Ee/Li, Da Wei/Moon, Yung In
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Abstract
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The effects of the dried fruit powder of Opuntia ficus-indica var. saboten (OF-f) were investigated on gastric lesion and ulcer models in rats. It showed significant inhibition in HCl-ethanol and HCl-aspirin induced gastric lesion at a dose of 600 ㎎/㎏, p.o. OF-f also showed significant inhibition in indomethacin induced gastric lesion at the doses of 200 and 600 ㎎/㎏, p.o. However, it did not affect aspirin and Shay ulcer in rats. It also did not affect the gastric juice secretion, acid output and pH. These data suggest that OF-f possesses pronounced inhibitory action on gastric lesion of rats.
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