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KMID : 0620720020080040183
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Natural Product Sciences
2002 Volume.8 No. 4 p.183 ~ p.185
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Inhibitory Effects of Hydrolysable Tannins on Tyrosinase Activities in B16 Mouse Melanoma Cells
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Cho, Soo Min
Kwon, Young Min/Lee, Jae Hee/Lee, Min Won
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Abstract
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To investigate skin whitening natural substances, the effects on melanogenesis by measuring the tyrosinase activity and the melanin contents of three hydrolysable tannins, 1,2,6-tri-O-galloyl-β-D-glucose (1), 2,3-(S)-HHDP-D-glucose (2) and pedunculagin (3) in B16 melanoma cells were examined. 1,2,6-Tri-O-galloyl-β-D-glucose (1), 2,3-(S)-HHDP-D-glucose (2) and pedunculagin (3) inhibited tyrosinase activity in B16 melanoma cells in a dose-dependent manner.
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