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KMID : 0620720030090030154
Natural Product Sciences
2003 Volume.9 No. 3 p.154 ~ p.157
Pharmacological Screening of Sesbania grandiflora L. Poiret Extracts
Subramanian, E. Harihara
Varghese, Shyju/Rameshkumar, N./Ilavarasan, R./Sridhar, S. K.
Abstract
In the present study, the roots of Sesbania grandiflora L. Poiret(Papilionaceae)were successively extracted with petroleum ehter (PE), chloroform (CE), methanol (ME) and water (AE) by soxhlet extraction. The extracts were vacuum dried and screened for analgesic for analgesic, antidiarrhoeal, antibacterial (Stahpylococcus epidermidis, Stahpylococcus aureus, Micrococcus luteus, Bacillus cereus, and Klebsiella pneumonia) and antifungal (Candida albicans and Aspergillus niger) activity. All the extracts exhibited potent, dose dependant (40 and 80 mg/kg) and significant analgesic and antidiarrhoeal activity in the order of AE>PE>CE>ME>PE>AE>CE respectively. AE at the experimental dose was found to exhibit more potent analgesic activity than the standard drug. All the extracts exhibited significant antibacterial (100 ?g/ml) and antifungal activity (50 and 100?g/ml). Me exhibited the most potent antibacterial activity.
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