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KMID : 0620720040100060335
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Natural Product Sciences
2004 Volume.10 No. 6 p.335 ~ p.340
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Phytochemical Constituents of the Aerial Parts from Aster hispidus
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Lee Sung-Ok
Choi Sang-Zin
Choi Sang-Un
Ryu Shi-Yong
Lee Kang-Ro
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Abstract
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The chromatographic separation of the MeOH extract of the aerial parts from Aster hispidus (Compositae) led to the isolation of eight compounds. Their structures were established by spectroscopic methods to be β-amyrin (1), oleanolic acid (2), (2R)-1, 2-O-(9Z, 12Z, 15Z-dioctadecatrienoyl)-3-O-β-D-galactopyranosyl glycerol (3), trans-phytol (4), 9, 12, 15-octadecatrienoic acid (5), kaempferol (6), 3,5-dicaffeoyl quinic acid (7), 3,4-dicaffeoyl quinic acid (8) and kaempferol-3-O-rutinoside (9). Compounds 1, 3 ~ 6 and 9 showed non-specific moderate cytotoxicity against five human tumor cell lines (5.44 ~ 23.51 ㎍/ml). The other compounds were of marginal activity against tested five human cancer cell lines $(9.05{\sim}>30.0\;{\mu}g/ml)$.
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KEYWORD
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Aster hispidus, Compositae, terpenoid, flavonoid, cytotoxicity
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