KMID : 0620720070130030186
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Natural Product Sciences 2007 Volume.13 No. 3 p.186 ~ p.189
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Phytochemical and Biological Studies on Verbascum sinaiticum Growing in Egypt
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Mahmoud Samia M.
Abdel-Azim Nahla S. Shahat Abdelaaty A. Ismail Shams I. Hammouda Faiza M.
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Abstract
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The aerial parts of Verbascum sinaiticum Benth. (Scrophulariaceae) yielded two iridoids that were idenified as ajugol 3 and aucubin 4. Also, investigation of the flavonoid constituents revealed the isolation and identification of luteolin 1 and chrysoeriol-7-glucoside 2. All the isolated compounds were identifid by spectroscopicmethods (UV, MS, 1H-NMR and 13C-NMR) and in comparison with the literature data. Both alcohol and methylene chloride/methanol extracts (1 : 1) exhibited a hepatoprotective effect by CCl4challenge test.
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KEYWORD
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Flavonoids, Hepatoprotection, Iridoides, Verbascum sinaiticum
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