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KMID : 0620720070130030229
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Natural Product Sciences
2007 Volume.13 No. 3 p.229 ~ p.233
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Nucleoside Constituents of the Egyptian Tunicate Eudistoma laysani
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Abou-Hussein Dina R.
Badr Jihan M.
Youssef Diaa T.A.
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Abstract
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Chemical investigation of the crude extract of the Egyptian marine tunicate Eudistoma laysani led to the isolation of a new nucleoside; 3-deazainosine and four known ones; inosine, 2’-deoxyuridine, adenosine and 2’-deoxyadenosine. Structural elucidation of the isolated compounds was based on intensive studies of their spectral data including 1D (1H and 13C) and 2D (1H-1H COSY, HMQC, HMBC) NMR together with mass spectra. The antioxidant effects of the isolated compounds were determined using DPPH, where they exhibited significant activities.
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KEYWORD
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Tunicates, Eudistoma laysani, nucleosides, spectroscopic techniques, antioxidant activity
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