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KMID : 0620720070130040300
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Natural Product Sciences
2007 Volume.13 No. 4 p.300 ~ p.303
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Cytotoxic and Antibacterial Activities of Gossypin
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Chamundeeswari D.
Sukumar Ethirajan
Amar K.
Reddy N. Brahmananda
Kumar I. Anil
Chowdry B.V.
Samatha K.
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Abstract
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Gossypin, a naturally occurring polyhydroxy flavonoid, when subjected to in vitro cytotoxic screening against vero cell lines exhibited 68.75% inhibition at a concentration of 1000㎍ . When tested against five bacteria and five fungi, the flavone derivative showed a moderate activity against Staphylococcus aureus and Escherichia coli, mild inhibition against Pseudomonas aerugenosa and Salmonella typhi and no activity against any of the tested fungi, in the concentrations studied.
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KEYWORD
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Gossypin, cytotoxicity, antibacterial activity
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